Welcome to Surgical Research

The research program of the Department of Surgery is among the most diverse at the University of Chicago. Scientists and surgeons in the Department conduct research on fundamental biology as well as specific diseases, including forms of cancer, disorders of the blood vessels, diabetes and heart abnormalities. Other work is focused on improving organ transplantation, developing novel synthetic materials for vaccines and regulation of the immune system, and understanding the role of the human microbiome, the population of bacteria that inhabits all of us, in illness and health. 

In addition to laboratory-based research, University of Chicago surgeons conduct multiple clinical studies to help develop new therapies. Opportunities to participate in these studies can be identified by following the Clinical Trials link on this website.

Feel free to explore the research of our faculty investigators and contact them if you would like to learn more.


Karl Matlin, PhD
Professor of Surgery
Vice Chairman of Research