Animal Microsurgery Center (CORE)

The Animal Microsurgery Center (Core) or AMC has been developed and affiliated with the Department of Surgery. This core will provide strategic leadership; serve as a liaison to academic departments, professional organizations, and administrative units of the University; manage operations, staffing, and program development of the Center; help set strategic goals; disseminate mouse and rat surgical techniques; train laboratory and clinical research personnel in surgical procedures in the rodents; and collaborate with Animal Resource Center to oversee the establishment of goals and operating procedures, practices, and guidelines for the Center. The AMC provides investigators with mouse and rat surgical models, including:

  • Transplantation models, including heart (first and secondary), kidney, pancreas, small bowel, liver, skin and islet
  • Ischemic model: kidney, liver and heart
  • Bariatric surgical procedures, including gastric banding, vertical sleeve gastrectomy, Roux-en-Y gastic bypass, DJB, biliopancreatic diversion with duodenal switch
  • Cardiovascular and metabolic models: myocardial infarction, aorta hypertention, A&V catheterizations
  • Cancer and immunological models: Barrett's esophagus, tumor implantation
  • General procedures: IV injection, splenectomy, nephrectomy, catheterization, blood glucose tests (GTT) and diabetic models
  • Develop surgical techniques and approaches according to the requirement by investigators.

Other AMC services include:

  • Microsurgical training for residency, clinical and research fellows and other staff who is interest in rodent surgical models internally and externally
  • Collaboration with scientists in the study of the pathogenesis and mechanisms of obesity, insulin resistance and diabetes, and immunology
  • Collaboration with the Animal Resource Care and other facilities (Cores) in development of surgical procedures

For more information, please contact:

Dengping Yin, MD, PhD
Director of Animal Microsurgery Center (Core)
5841 S. Maryland Ave, Chicago, IL 60637
SBRI J547/MC5026, Department of Surgery
(773) 702-5520